Have a deep breath!
In 2012, a study at the University of California, San Francisco (UCSF) calculated that even smoking just one joint everyday for 20 years may be benign, though most participants only smoked 2 or 3 joints each month. “I was surprised we didn’t see effects [of marijuana use],” said UCSF epidemiologist Mark Pletcher, who led the study.
One assessment of numerous epidemiological studies points to small sample size and poor study design as reasons for scientists’inability to nail down a link between cannabis and cancer risk. However, many suspect that this type of link doesn’t exist, and that marijuana might even have cancer-preventive effects. A 2008 study, like, suggested that smoking marijuana may reduce the danger of tobacco-associated lung cancer, calculating that folks who smoke both marijuana and tobacco have a lesser danger of cancer than those that smoke only tobacco (though still a greater risk than non-smokers).
But even Pletcher isn’t sanguine about marijuana’s effects on the lungs, and suspects that there may be long-term lung damage which can be hard to detect. Are 3000mg CBD Gummies very powerful? “We really can’t reassure ourselves about heavy use,” he explained.
Your brain on drugs
There’s some evidence to suggest that stoned subjects exhibit increased risk-taking and impaired decision-making, and score worse on memory tasks-and residual impairments have been detected days as well as weeks after use. Some studies also link years of regular marijuana use to deficits in memory, learning, and concentration. A current and widely discussed report on the IQs of New Zealanders followed since birth discovered that cannabis users who’d started their habit in adolescence had lower IQs than non-users.
In this study, led by researchers at Duke University, “you could clearly see as a consequence of cannabis use, IQ falls,” said Derik Hermann, a clinical neuroscientist at the Central Institute of Mental Health in Germany who was not involved in the research.
But not 4 months later, a re-analysis and computer simulation at the Ragnar Frisch Center for Economic Research in Oslo countered the Duke findings. Ole Rogeberg contended that socioeconomic factors, not marijuana use, contributed to the reduced IQs noticed in cannabis users.
Rogeberg’s conclusion counters a substantial literature, however, which supports a link between pot use and neurophysiological decline. Studies in both humans and animals suggest that folks who acquiring a marijuana habit in adolescence face long-term negative impacts on brain function, with some users finding it difficult to concentrate and learn new tasks.
Notably, most studies on the subject suggest that while there may be negative consequences of smoking as a teen, users who begin in adulthood are usually unaffected. This might be as a result of endocannabinoid-directed reorganization of the mind during puberty, Hermann explained. The intake of cannabinoids that is included with pot use might cause irreversible “misleading of the neural growth,” he said.
Along with the consequences for intelligence, many studies suggest that smoking marijuana raises the danger of schizophrenia, and could have similar effects on the brain. Hermann’s group used MRI to detect cannabis-associated neuron damage in the pre-frontal cortex and found so it was similar to brain changes noticed in schizophrenia patients. Other studies further suggest that weed-smoking schizophrenics have greater disease-associated brain changes and perform worse on cognitive tests than their non-smoking counterparts.
But much with this research can’t distinguish between brain changes caused by marijuana use and symptoms related to the disease. It’s possible that cannabis-smoking schizophrenics “might have unpleasant symptoms [that precede full-blown schizophrenia] and are self-medicating” with the psychotropic drug, said Roland Lamarine, a professor of community health at California State University, Chico. “We haven’t seen a rise in schizophrenics, despite much more marijuana use.”
In reality, other research shows that cannabis-using schizophrenics score better on cognitive tests than non-using schizophrenics. Such conflicting reports may be because of the varying concentrations-and varying effects-of cannabinoids in marijuana. Along with tetrahydrocannabinol (THC), a neurotoxic cannabinoid that’s in charge of marijuana’s mind-altering properties, the drug also incorporates many different non-psychoactive cannabinoids, including cannabidiol (CBD), which could force away neuron damage. Hermann discovered that the volume of the hippocampus-a brain area important for memory processing-is slightly smaller in cannabis users than in non-users, but more CBD-rich marijuana countered this effect.
A lethal cocktail?
While data supporting the harmful ramifications of marijuana by itself are weak, some researchers are far more concerned about the drug in conjunction with other substances, such as tobacco, alcohol, or cocaine. Some studies suggest, like, that marijuana may increase cravings for other drugs, leading to its infamous tag as a “gateway drug.” A study published earlier this month supported this theory when it discovered that, at least in rats, THC exposure increases tobacco’s addictive effects. Furthermore, marijuana might not mix well with prescription drugs, as cannabis causes the liver to metabolize drugs more slowly, raising the danger of drug toxicity.